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Proceedings Paper

Photo-nano-therapy for bactericidal using graphene oxide
Author(s): Jie Wu; Jinchao Gao M.D.; Yujia Xie; Xianpei Chen
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Paper Abstract

Graphene oxide (GO) have attracted more attention because of the universal property, and rapidly applied in biomedical field, such as drug carriers, imaging or therapy. GO has been considered biocompatible with a broad variety of eukaryotic cells. Here, we show that, GO could kill Gram-positive and –negative bacteria rapidly and efficiently, with light irradiation. We investigated the efficacy of GO on bactericidal activation, the antibacterial activity of GO is concentration dependent, and enhanced by light irradiation. Our results describe the discovery of a property of partially GO as a potent antibacterial agent. The results showed that GO has excellent antibacterial activity when the concentration is above 300 μg/mL, the antibacterial rate can reached 100% when incubated with E. coli and B. subtilis for 4h.

Paper Details

Date Published: 9 March 2015
PDF: 8 pages
Proc. SPIE 9324, Biophotonics and Immune Responses X, 93240Z (9 March 2015); doi: 10.1117/12.2079438
Show Author Affiliations
Jie Wu, Beijing Normal Univ. (China)
Jinchao Gao M.D., Beijing Normal Univ. (China)
Yujia Xie, Beijing Normal Univ. (China)
Xianpei Chen, Beijing Normal Univ. (China)

Published in SPIE Proceedings Vol. 9324:
Biophotonics and Immune Responses X
Wei R. Chen, Editor(s)

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