Accurate modeling and efficient calculation of photon migration in biological tissues is requested for determination of the optical properties of living tissues by in vivo experiments. This study develops a calculation scheme of photon migration for determination of the optical properties of the rat cerebral cortex (ca 0.2 cm thick) based on the three-dimensional time-dependent radiative transport equation assuming a homogeneous object. It is shown that the time-resolved profiles calculated by the developed scheme agree with the profiles measured by in vivo experiments using near infrared light. Also, an efficient calculation method is tested using the delta-Eddington approximation of the scattering phase function.

Date Published: 10 March 2015
PDF: 6 pages
Proc. SPIE 9333, Biomedical Applications of Light Scattering IX, 933313 (10 March 2015); doi: 10.1117/12.2079265

Published in SPIE Proceedings Vol. 9333:
Biomedical Applications of Light Scattering IX
Adam Wax; Vadim Backman, Editor(s)