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Proceedings Paper

Photoacoustic tomography of the human finger: towards the assessment of inflammatory joint diseases
Author(s): P. van Es; S. K. Biswas; Hein J. Bernelot Moens; W. Steenbergen; Srirang Manohar
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Paper Abstract

Inflammatory arthritis is often manifested in finger joints. The growth of new or withdrawal of old blood vessels can be a sensitive marker for these diseases. Photoacoustic (PA) imaging has great potential in this respect since it allows the sensitive and highly resolved visualization of blood. We systematically investigated PA imaging of finger vasculature in healthy volunteers using a newly developed PA tomographic system. We present the PA results which show excellent detail of the vasculature. Vessels with diameters ranging between 100 μm and 1.5 mm are visible along with details of the skin, including the epidermis and the subpapillary plexus. The focus of all the studies is at the proximal and distal interphalangeal joints, and in the context of ultimately visualizing the inflamed synovial membrane in patients. This work is important in laying the foundation for detailed research into PA imaging of the phalangeal vasculature in patients suffering from rheumatoid arthritis.

Paper Details

Date Published: 11 March 2015
PDF: 5 pages
Proc. SPIE 9323, Photons Plus Ultrasound: Imaging and Sensing 2015, 93234Q (11 March 2015); doi: 10.1117/12.2078676
Show Author Affiliations
P. van Es, Univ. Twente (Netherlands)
S. K. Biswas, Univ. Twente (Netherlands)
Indian Institute of Science (India)
Hein J. Bernelot Moens, Hospital Group Twente (Netherlands)
W. Steenbergen, Univ. Twente (Netherlands)
Srirang Manohar, Univ. Twente (Netherlands)

Published in SPIE Proceedings Vol. 9323:
Photons Plus Ultrasound: Imaging and Sensing 2015
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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