A Raman imaging system which combined a hollow fiber bundle and a direct imaging technique was constructed for high-speed endoscopic Raman imaging. The hollow fiber bundle is fabricated by depositing a silver thin film on the inner surface of pre-drawn glass capillary bundle. It performs as a fiber optic probe which transmits a Raman image with high signal-to-noise ratio because the propagating light is confined into the air core inducing little light scattering. The field of view on the sample is uniformly irradiated by the excitation laser light via the probe. The back-scattered image is collected by the probe and captured directly by an image sensor. A pair of thin film tunable filters is used to select target Raman band. This imaging system enables flexible and high-speed Raman imaging of biological tissues.

Date Published: 11 March 2015
PDF: 5 pages
Proc. SPIE 9317, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XV, 93170V (11 March 2015); doi: 10.1117/12.2078662

Published in SPIE Proceedings Vol. 9317:
Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XV
Israel Gannot, Editor(s)