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Proceedings Paper

Full-field optical coherence tomography (FFOCT) for evaluation of endometrial cancer
Author(s): Alexis Bruhat; Marais Combrinck; Eugénie Dalimier; Fabrice Harms; Jeffrey L. Fine
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Paper Abstract

Full-field optical coherence tomography (FFOCT) quickly produces images that resemble conventional pathology images. We examined endometrium in an intra-operative like fashion (more than forty samples). FFOCT-imaged endometrium was recognizable to pathologists and compared favorably with microscopy of the same samples. Additional image enhancements and acquisition techniques were explored and may improve interpretation accuracy. Wider evaluation of images is ongoing, using more pathologist subjects. FFOCT may revolutionize pathology practice in the future by permitting rapid diagnosis and in vivo diagnosis; this is potentially a disruptive new diagnostic technique in pathology.

Paper Details

Date Published: 26 February 2015
PDF: 8 pages
Proc. SPIE 9303, Photonic Therapeutics and Diagnostics XI, 93032Y (26 February 2015); doi: 10.1117/12.2078537
Show Author Affiliations
Alexis Bruhat, Univ. of Pittsburgh School of Medicine (United States)
Marais Combrinck, PathWest Lab. Medicine WA (Australia)
Eugénie Dalimier, LLTech SAS (France)
Fabrice Harms, LLTech SAS (France)
Jeffrey L. Fine, Univ. of Pittsburgh School of Medicine (United States)

Published in SPIE Proceedings Vol. 9303:
Photonic Therapeutics and Diagnostics XI
Hyun Wook Kang; Brian J. F. Wong M.D.; Melissa C. Skala; Bernard Choi; Guillermo J. Tearney M.D.; Andreas Mandelis; Nikiforos Kollias; Kenton W. Gregory M.D.; Mark W. Dewhirst D.V.M.; Justus F. Ilgner M.D.; Alfred Nuttal; Haishan Zeng; Laura Marcu; Claus-Peter Richter, Editor(s)

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