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Proceedings Paper

Simultaneous optical and mechanical probes to investigate complex cellular responses to physical cues
Author(s): Kristina Haase; Zeinab Al-Rekabi; Louise Guolla; Ryan Hickey; Dominique Tremblay; Andrew E. Pelling
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Paper Abstract

Living cells possess an exquisite ability to sense and respond to physical information in their microenvironment. This ability plays a key role in many fundamentally important physiological and pathological processes. We will describe our work utilizing a variety of biophysical tools to investigate the dynamic responses of cells to mechanical stimuli and how physical cues can be employed to re-purpose and manipulate biological processes. These responses to physical cues are not simply a side-product of biology but are key components of biological and physical feedback loops that govern the life of a cell.

Paper Details

Date Published: 6 March 2015
PDF: 11 pages
Proc. SPIE 9327, Optical Elastography and Tissue Biomechanics II, 93270I (6 March 2015); doi: 10.1117/12.2078336
Show Author Affiliations
Kristina Haase, Univ. of Ottawa (Canada)
Zeinab Al-Rekabi, Univ. of Ottawa (Canada)
Univ. of Washington (United States)
Louise Guolla, Univ. of Ottawa (Canada)
Ryan Hickey, Univ. of Ottawa (Canada)
Dominique Tremblay, Univ. of Ottawa (Canada)
Andrew E. Pelling, Univ. of Ottawa (Canada)

Published in SPIE Proceedings Vol. 9327:
Optical Elastography and Tissue Biomechanics II
Kirill V. Larin; David D. Sampson, Editor(s)

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