
Proceedings Paper
Assessment of cutaneous melanoma and pigmented skin lesions with photoacoustic imagingFormat | Member Price | Non-Member Price |
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Paper Abstract
Melanoma is the most dangerous form of skin cancer and is the most difficult to diagnose and stage. Knowing
the thickness of melanoma and its level of invasion into cutaneous tissue is the most important factor [1, 2] in
determining a patient’s prognosis [3, 4]. Detection of melanoma is typically done by clinical inspection of
lesion morphology, followed by lesion excision and histological assessment of the resected specimen. To
improve assessment and diagnosis of melanoma and other pigmented lesions, various non-invasive imaging
techniques, including photoacoustic (PA) imaging, have been investigated. PA imaging is a non-invasive
imaging modality which combines laser light with ultrasound, and can be used to image pigmented skin lesion
morphology [5-7] due the high absorption of melanin in the visible and near-infrared wavelength rage. In this
study we investigate the clinical usefulness of PA imaging in diagnosing and assessing pigmented skin lesions
such as melanoma and melanocytic nevi. Pre-operative PA images of patients with suspected cases of cutaneous
melanoma were taken with the Vevo Lazr® 2100 PA imaging system at several wavelengths. The distribution
and maximum thickness of suspect lesions was determined by imaging at 700 nm, and the surrounding
vasculature was imaged at 900 nm. Information obtained from the PA images was compared with histological
examination of resected surgical specimens.
Paper Details
Date Published: 9 March 2015
PDF: 5 pages
Proc. SPIE 9303, Photonic Therapeutics and Diagnostics XI, 930303 (9 March 2015); doi: 10.1117/12.2078309
Published in SPIE Proceedings Vol. 9303:
Photonic Therapeutics and Diagnostics XI
Hyun Wook Kang; Brian J. F. Wong M.D.; Melissa C. Skala; Bernard Choi; Guillermo J. Tearney M.D.; Andreas Mandelis; Nikiforos Kollias; Kenton W. Gregory M.D.; Mark W. Dewhirst D.V.M.; Justus F. Ilgner M.D.; Alfred Nuttal; Haishan Zeng; Laura Marcu; Claus-Peter Richter, Editor(s)
PDF: 5 pages
Proc. SPIE 9303, Photonic Therapeutics and Diagnostics XI, 930303 (9 March 2015); doi: 10.1117/12.2078309
Show Author Affiliations
Aedán Breathnach, National Univ. of Ireland, Galway (Ireland)
Liz Concannon, Galway Univ. Hospitals (Ireland)
Laura Aalto, Univ. College Hospital Galway (Ireland)
Jemima Dorairaj, Galway Univ. Hospital (Ireland)
Liz Concannon, Galway Univ. Hospitals (Ireland)
Laura Aalto, Univ. College Hospital Galway (Ireland)
Jemima Dorairaj, Galway Univ. Hospital (Ireland)
Hrehesh M. Subhash, National Univ. of Ireland, Galway (Ireland)
Jack Kelly, Galway Univ. Hospital (Ireland)
Martin J. Leahy, National Univ. of Ireland, Galway (Ireland)
Royal College of Surgeons (Ireland)
Jack Kelly, Galway Univ. Hospital (Ireland)
Martin J. Leahy, National Univ. of Ireland, Galway (Ireland)
Royal College of Surgeons (Ireland)
Published in SPIE Proceedings Vol. 9303:
Photonic Therapeutics and Diagnostics XI
Hyun Wook Kang; Brian J. F. Wong M.D.; Melissa C. Skala; Bernard Choi; Guillermo J. Tearney M.D.; Andreas Mandelis; Nikiforos Kollias; Kenton W. Gregory M.D.; Mark W. Dewhirst D.V.M.; Justus F. Ilgner M.D.; Alfred Nuttal; Haishan Zeng; Laura Marcu; Claus-Peter Richter, Editor(s)
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