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Proceedings Paper

Reducing the formation of image artifacts during spectroscopic micro-CT acquisitions
Author(s): Marcus Zuber; Thomas Koenig; Rubaiya Hussain; Elias Hamann; Rafael Ballabriga; Michael Campbell; Alex Fauler; Michael Fiederle; Tilo Baumbach
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Paper Abstract

Spectroscopic micro-computed tomography using photon counting detectors is a technology that promises to deliver material-specific images in pre-clinical research. Inherent to such applications is the need for a high spatial resolution, which can only be achieved with small focal spot sizes in the micrometer range. This limits the achievable x-ray fluxes and implies long acquisitions easily exceeding one hour, during which it is paramount to maintain a constant detector response. Given that photon-counting detectors are delicate systems, with each pixel hosting advanced analog and digital circuitry, this can represent a challenging task. In this contribution, we illustrate our findings on how to reduce image artifacts in computed tomography reconstructions under these conditions, using a Medipix3RX detector featuring a cadmium telluride sensor. We find that maintaining a constant temperature is a prerequisite to guarantee energy threshold stability. More importantly, we identify varying sensor leakage currents as a significant source to artifact formation. We show that these leakage currents can render the corresponding images unusable if the ambient temperature fluctuates, as caused by an air conditioning, for example. We conclude with demonstrating the necessity of an adjustable leakage current compensation.

Paper Details

Date Published: 18 March 2015
PDF: 12 pages
Proc. SPIE 9412, Medical Imaging 2015: Physics of Medical Imaging, 94124X (18 March 2015); doi: 10.1117/12.2077685
Show Author Affiliations
Marcus Zuber, Karlsruhe Institute of Technology (KIT) (Germany)
Thomas Koenig, Karlsruhe Institute of Technology (KIT) (Germany)
Rubaiya Hussain, Karlsruhe Institute of Technology (KIT) (Germany)
Elias Hamann, Karlsruhe Institute of Technology (KIT) (Germany)
Rafael Ballabriga, European Organization for Nuclear Research (CERN) (Switzerland)
Michael Campbell, European Organization for Nuclear Research (CERN) (Switzerland)
Alex Fauler, Freiburg Materials Research Ctr. (Germany)
Michael Fiederle, Karlsruhe Institute of Technology (KIT) (Germany)
Freiburg Materials Research Ctr. (Germany)
Tilo Baumbach, Karlsruhe Institute of Technology (KIT) (Germany)

Published in SPIE Proceedings Vol. 9412:
Medical Imaging 2015: Physics of Medical Imaging
Christoph Hoeschen; Despina Kontos, Editor(s)

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