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Proceedings Paper

Retrieving small features in reflection-mode raster-scan optoacoustic mesoscopy (RSOM) using multi-frequency reconstruction
Author(s): Murad Omar; Dominik Soliman; Jérôme Gateau; Vasilis Ntziachristos
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Paper Abstract

We developed a reflection-mode, raster-scan optoacoustic mesoscopy system, based on a custom-made ultrasonic detector, with an ultra wide bandwidth of 20-180 MHz. To optimally use this bandwidth, we implemented multifrequency reconstruction. System characterization reveals a 4 μm axial, and 18 μm transverse resolution, at penetration depths reaching 5 mm. After characterization, the system was applied to image a zebrafish ex vivo, and an excised mouse ear. In the zebrafish, the lateral line, intestines, eyes, and melanocytes are seen, while in the mouse ear, multi-frequency reconstruction recovered the small vessels, otherwise not seen on the image.

Paper Details

Date Published: 11 March 2015
PDF: 6 pages
Proc. SPIE 9323, Photons Plus Ultrasound: Imaging and Sensing 2015, 932326 (11 March 2015); doi: 10.1117/12.2076717
Show Author Affiliations
Murad Omar, TU Muenchen (Germany)
HelmholtzZentrum Muenchen (Germany)
Dominik Soliman, TU Muenchen (Germany)
HelmholtzZentrum Muenchen (Germany)
Jérôme Gateau, Institut Langevin (France)
Vasilis Ntziachristos, TU Muenchen (Germany)
HelmholtzZentrum Muenchen (Germany)

Published in SPIE Proceedings Vol. 9323:
Photons Plus Ultrasound: Imaging and Sensing 2015
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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