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Proceedings Paper

Photoacoustic signal simulation and detection optimization based on laser-scanning optical-resolution photoacoustic microscopy
Author(s): Lin Li; Yi Du; Qingliang Zhao; Qian Li; Xinyu Chai; Chuanqing Zhou
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Paper Abstract

Laser-scanning optical-resolution photoacoustic microscopy (LSOR-PAM) has a high application potential in ophthalmology and other clinical fields because of its high resolution and imaging speed. The stationary unfocused ultrasonic transducer of this system decides the efficiency and field of view (FOV) of photoacoustic signal detection, but the refraction and attenuation of laser generated photoacoustic signal in different tissue mediums will cause signal strength and direction distribution uneven. In this study, we simulated the photoacoustic signal propagation and detection in compound medium models with different tissue parameters using k-space method based on LSOR-PAM imaging principle. The results show a distance related signal strength attenuation and FOV changes related to transducer angle. Our study provides a method for photoacoustic signal detection optimization for different complex tissue structure with LSOR-PAM.

Paper Details

Date Published: 20 November 2014
PDF: 7 pages
Proc. SPIE 9268, Optics in Health Care and Biomedical Optics VI, 92682R (20 November 2014); doi: 10.1117/12.2073627
Show Author Affiliations
Lin Li, Shanghai Jiao Tong Univ. (China)
Yi Du, Shanghai Jiao Tong Univ. (China)
Qingliang Zhao, Shanghai Jiao Tong Univ. (China)
Qian Li, Shanghai Jiao Tong Univ. (China)
Xinyu Chai, Shanghai Jiao Tong Univ. (China)
Chuanqing Zhou, Shanghai Jiao Tong Univ. (China)

Published in SPIE Proceedings Vol. 9268:
Optics in Health Care and Biomedical Optics VI
Qingming Luo; Xingde Li; Ying Gu; Yuguo Tang, Editor(s)

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