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Proceedings Paper

Using micro and nanofluidics with surface enhanced Raman spectroscopy for in vitro blood based biomarker detection
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Paper Abstract

In this presentation we will discuss the development of a point-of-care optofluidic device that uses gold nanoparticlebased surface enhanced Raman spectroscopy (SERS) for detection of blood biomarkers. SERS approaches have been successfully used for detection of analytes due to the large enhancements provided by the interaction between the light, gold particles, and analyte. However, SERS approaches developed for use to accurately quantify an analyte have suffered from a lack of repeatability. We will describe our SERS optofluidic device with functionalized nanoparticles that helps to overcome these problems and will show results with a focus on blood cardiac biomarkers.

Paper Details

Date Published: 19 May 2014
PDF: 5 pages
Proc. SPIE 9155, Translational Biophotonics, 91550E (19 May 2014); doi: 10.1117/12.2065418
Show Author Affiliations
Gerard L Coté, Texas A&M Univ. (United States)
Jun Kameoka, Texas A&M Univ. (United States)
Haley Marks, Texas A&M Univ. (United States)

Published in SPIE Proceedings Vol. 9155:
Translational Biophotonics
Tomasz S. Tkaczyk, Editor(s)

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