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Proceedings Paper

A portable surface plasmon resonance biosensor capable of phase interrogation in a large dynamic range
Author(s): How-Foo Chen; Hsin-Yuan Chuang; Chih-Hang Chen; Yun-Hsiang Chang
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Paper Abstract

With the development of a point of care (POC) biosensor in mind, a polymer-molding prism with double parabolic surfaces is invented and developed to implement an ultra-compact SPR biosensor with extremely high sensitivity. The polymer molded parabolic prism is cost effective and disposable, thus cross contamination between biological samples can be avoided. A highly sensitive biosensor with a form factor less than 15cm*15cm*5cm was received with a tunable excitation angle of light beam for a large dynamic range. A highly sensitive optical phase interrogation was demonstrated. The biosensor is also compatible to a modern microscopy platform.

Paper Details

Date Published: 27 August 2014
PDF: 6 pages
Proc. SPIE 9166, Biosensing and Nanomedicine VII, 91660Q (27 August 2014); doi: 10.1117/12.2061732
Show Author Affiliations
How-Foo Chen, National Yang-Ming Univ. (Taiwan)
Hsin-Yuan Chuang, National Yang-Ming Univ. (Taiwan)
Chih-Hang Chen, National Yang-Ming Univ. (Taiwan)
Yun-Hsiang Chang, National Yang-Ming Univ. (Taiwan)

Published in SPIE Proceedings Vol. 9166:
Biosensing and Nanomedicine VII
Hooman Mohseni; Massoud H. Agahi; Manijeh Razeghi, Editor(s)

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