
Proceedings Paper
Combined Raman spectroscopy and autofluoresence imaging method for in vivo skin tumor diagnosisFormat | Member Price | Non-Member Price |
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Paper Abstract
The fluorescence and Raman spectroscopy (RS) combined method of in vivo detection of malignant human skin cancer
was demonstrated. The fluorescence analysis was used for detection of abnormalities during fast scanning of large tissue
areas. In suspected cases of malignancy the Raman spectrum analysis of biological tissue was performed to determine
the type of neoplasm. A special RS phase method was proposed for in vivo identification of skin tumor. Quadratic
Discriminant Analysis was used for tumor type classification on phase planes. It was shown that the application of phase
method provides a diagnosis of malignant melanoma with a sensitivity of 89% and a specificity of 87%.
Paper Details
Date Published: 5 September 2014
PDF: 8 pages
Proc. SPIE 9198, Ultrafast Nonlinear Imaging and Spectroscopy II, 919804 (5 September 2014); doi: 10.1117/12.2061667
Published in SPIE Proceedings Vol. 9198:
Ultrafast Nonlinear Imaging and Spectroscopy II
Zhiwen Liu, Editor(s)
PDF: 8 pages
Proc. SPIE 9198, Ultrafast Nonlinear Imaging and Spectroscopy II, 919804 (5 September 2014); doi: 10.1117/12.2061667
Show Author Affiliations
V. P. Zakharov, Samara State Aerospace Univ. (Russian Federation)
I. A. Bratchenko, Samara State Aerospace Univ. (Russian Federation)
O. O. Myakinin, Samara State Aerospace Univ. (Russian Federation)
D. N. Artemyev, Samara State Aerospace Univ. (Russian Federation)
I. A. Bratchenko, Samara State Aerospace Univ. (Russian Federation)
O. O. Myakinin, Samara State Aerospace Univ. (Russian Federation)
D. N. Artemyev, Samara State Aerospace Univ. (Russian Federation)
Y. A. Khristoforova, Samara State Aerospace Univ. (Russian Federation)
S. V. Kozlov, Samara State Medical Univ. (Russian Federation)
A. A. Moryatov, Samara State Medical Univ. (Russian Federation)
S. V. Kozlov, Samara State Medical Univ. (Russian Federation)
A. A. Moryatov, Samara State Medical Univ. (Russian Federation)
Published in SPIE Proceedings Vol. 9198:
Ultrafast Nonlinear Imaging and Spectroscopy II
Zhiwen Liu, Editor(s)
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