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Proceedings Paper

Left and right topography of F-actin filaments
Author(s): Leda Chang; Fransiska S. Franke; Paula Flicker; David Keller
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Paper Abstract

F-actin filaments have been found to adopt conformations with both right handed and left handed topographies, as revealed by AFM imaging in air. The left handed conformation has not been observed previously by either AFM or electron microscopy. Either handedness can be produced by controlling the conditions under which the molecules are deposited for imaging by Scanning Force Microscopy or Transmission Electron Microscopy. Low salt conditions favor the left handed form, and high salt conditions favor the right handed form. The ability of F-actin to undergo larger changes may still reflect smaller changes that take place under physiological conditions.

Paper Details

Date Published: 30 March 1995
PDF: 6 pages
Proc. SPIE 2384, Scanning Probe Microscopies III, (30 March 1995); doi: 10.1117/12.205937
Show Author Affiliations
Leda Chang, Univ. of New Mexico (United States)
Fransiska S. Franke, Univ. of New Mexico (United States)
Paula Flicker, Vanderbilt Univ. (United States)
David Keller, Univ. of New Mexico (United States)

Published in SPIE Proceedings Vol. 2384:
Scanning Probe Microscopies III
Mehdi Vaez-Iravani, Editor(s)

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