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Proceedings Paper

Design and synthesis of a fluorescent molecular imprinted polymer for use in an optical fibre-based cocaine sensor
Author(s): Stephen P. Wren; Sergey A. Piletsky; Kal Karim; Paul Gascoine; Richard Lacey; Tong Sun; Kenneth T. V. Grattan
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Paper Abstract

Previously, we have developed chemical sensors using fibre optic-based techniques for the detection of Cocaine, utilising molecularly imprinted polymers (MIPs) containing fluorescein moieties as the signalling groups. Here, we report the computational design of a fluorophore which was incorporated into a MIP for the generation of a novel sensor that offers improved sensitivity for Cocaine with a detection range of 1-100μM. High selectivity for Cocaine over a suite of known Cocaine interferants (25μM) was also demonstrated by measuring changes in the intensity of fluorescence signals received from the sensor.

Paper Details

Date Published: 2 June 2014
PDF: 4 pages
Proc. SPIE 9157, 23rd International Conference on Optical Fibre Sensors, 91574W (2 June 2014); doi: 10.1117/12.2059278
Show Author Affiliations
Stephen P. Wren, City Univ. London (United Kingdom)
Sergey A. Piletsky, Cranfield Univ. (United Kingdom)
Univ. of Leicester (United Kingdom)
Kal Karim, Cranfield Univ. (United Kingdom)
Univ. of Leicester (United Kingdom)
Paul Gascoine, Smiths Detection (United Kingdom)
Richard Lacey, Ctr. for Applied Science and Technology (United Kingdom)
Tong Sun, City Univ. London (United Kingdom)
Kenneth T. V. Grattan, City Univ. London (United Kingdom)

Published in SPIE Proceedings Vol. 9157:
23rd International Conference on Optical Fibre Sensors
José M. López-Higuera; Julian D. C. Jones; Manuel López-Amo; José Luis Santos, Editor(s)

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