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Proceedings Paper

Serum and salivary cardiac analytes in acute myocardial infarction related to oral health status
Author(s): Jeffrey L. Ebersole; Richard J. Kryscio; Charles Campbell; Denis F. Kinane; John T. McDevitt; Nicolaos Christodoulides; Pierre N. Floriano; Craig S. Miller
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Paper Abstract

With the advent of an increased emphasis on the potential to utilize biomarkers in saliva for systemic diseases, the issue of existing oral disease is an important consideration that could adversely affect the interpretation of diagnostic results obtained from saliva. We addressed the question does a patient’s oral inflammation status confound biomarker levels used in diagnosis of acute myocardial infarction (AMI). The results demonstrated that multiple serum biomarkers and a few salivary biomarkers reflected the cardiac event. Importantly, oral health of the individual had minimal impact on the validity of the serum or salivary biomarker effectiveness.

Paper Details

Date Published: 5 June 2014
PDF: 8 pages
Proc. SPIE 9112, Sensing Technologies for Global Health, Military Medicine, and Environmental Monitoring IV, 91120G (5 June 2014); doi: 10.1117/12.2058734
Show Author Affiliations
Jeffrey L. Ebersole, Univ. of Kentucky (United States)
Richard J. Kryscio, Univ. of Kentucky (United States)
Charles Campbell, Univ. of Kentucky (United States)
Denis F. Kinane, Univ. of Pennsylvania (United States)
John T. McDevitt, Rice Univ. (United States)
Nicolaos Christodoulides, Rice Univ. (United States)
Pierre N. Floriano, Rice Univ. (United States)
Craig S. Miller, Univ. of Kentucky (United States)

Published in SPIE Proceedings Vol. 9112:
Sensing Technologies for Global Health, Military Medicine, and Environmental Monitoring IV
Šárka O. Southern; Mark A. Mentzer; Isaac Rodriguez-Chavez; Virginia E. Wotring, Editor(s)

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