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Proceedings Paper

Frequency-selective quantification of skin perfusion behavior during allergic testing using photoplethysmography imaging
Author(s): Nikolai Blanik; Claudia Blazek; Carina Pereira; Vladimir Blazek; Steffen Leonhardt
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Paper Abstract

Diagnosis of allergic immediate-type reactions is dependent on the visual assessment of the attending physician. With our novel non-obtrusive, camera-based photoplethysmography imaging (PPGI) setup, perfusion in the allergic testing area can be quantified and results displayed with spatial resolution in functional mappings. Thereby, each PPGI camera pixel can be assumed to be a classical (skin-based) reflective mode PPG sensor. An algorithm for post-processing of collected PPGI video sequences was developed to transfer black-and-white PPGI images into virtual 3D perfusion maps. For the first time, frequency selected perfusion quantification was assessed. For the presented evaluation, PPGI data from our clinical study were used [1]. For this purpose, different concentrations of histamine dilutions were administered to 27 healthy volunteers. Our results show clear trends in an increase in heartbeat synchronous perfusion rhythms and, simultaneously, a decrease of lower frequency vasomotor rhythms in these areas. These results, published for the first time, allow new insight into the distribution of skin perfusion dynamics and demonstrate the intuitive clinical usability of the proposed system.

Paper Details

Date Published: 21 March 2014
PDF: 6 pages
Proc. SPIE 9034, Medical Imaging 2014: Image Processing, 903429 (21 March 2014); doi: 10.1117/12.2043567
Show Author Affiliations
Nikolai Blanik, RWTH Aachen Univ. (Germany)
Claudia Blazek, Kantonsspital Aarau AG (Switzerland)
Carina Pereira, RWTH Aachen Univ. (Germany)
Vladimir Blazek, RWTH Aachen Univ. (Germany)
Steffen Leonhardt, RWTH Aachen Univ. (Germany)

Published in SPIE Proceedings Vol. 9034:
Medical Imaging 2014: Image Processing
Sebastien Ourselin; Martin A. Styner, Editor(s)

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