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Proceedings Paper

A feasibility study of carotid elastography for risk assessment of atherosclerotic plaques validated by magnetic resonance imaging
Author(s): Xiaochang Pan; Lingyun Huang; Manwei Huang; Xihai Zhao; Le He; Chun Yuan; Jing Bai; Jianwen Luo
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Paper Abstract

Stroke is a leading cause of mortality worldwide. One of its main reasons is rupture of carotid atherosclerotic plaques. Conventional B-mode ultrasound images and Doppler/color flow measurements are mostly used to evaluate degree of stenosis, which underestimates plaque vulnerability. Alternatively, the correspondence between multi-contrast magnetic resonance imaging (MRI) features, plaque composition and histology has been well established. In this study, the feasibility of ultrasound carotid elastography in risk assessment of carotid atherosclerotic plaques is investigated. Preliminarily in-vivo results on a small number of human subjects are initially validated by multi-contrast, highresolution MRI, and it shows that maximum strain rate might be feasible to evaluate the plaque vulnerability.

Paper Details

Date Published: 20 March 2014
PDF: 7 pages
Proc. SPIE 9040, Medical Imaging 2014: Ultrasonic Imaging and Tomography, 904002 (20 March 2014); doi: 10.1117/12.2042756
Show Author Affiliations
Xiaochang Pan, Tsinghua Univ. (China)
Lingyun Huang, Philips Research (China)
Manwei Huang, Meitan General Hospital (China)
Xihai Zhao, Tsinghua Univ. (China)
Le He, Tsinghua Univ. (China)
Chun Yuan, Tsinghua Univ. (China)
Univ. of Washington (United States)
Jing Bai, Tsinghua Univ. (China)
Jianwen Luo, Tsinghua Univ. (China)

Published in SPIE Proceedings Vol. 9040:
Medical Imaging 2014: Ultrasonic Imaging and Tomography
Johan G. Bosch; Marvin M. Doyley, Editor(s)

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