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Proceedings Paper

Polymer slab waveguides for the optical detection of nanoparticles in evanescent field based biosensors
Author(s): Nuria Teigell Beneitez; Jeroen Missinne; Jean Schleipen; Joke Orsel; Menno W. J. Prins; Geert Van Steenberge
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Paper Abstract

We present a polymer optical waveguide integration technology for the detection of nanoparticles in an evanescent field based biosensor. In the proposed biosensor concept, super-paramagnetic nanoparticles are used as optical contrast labels. The nanoparticles capture target molecules from a sample fluid and bind to the sensor surface with biological specificity. The surface-bound nanoparticles are then detected using frustration of an evanescent field. In the current paper we elaborate on the polymer waveguides which are used to generate a well-defined optical field for nanoparticle detection.

Paper Details

Date Published: 20 February 2014
PDF: 7 pages
Proc. SPIE 8954, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XI, 89540Q (20 February 2014); doi: 10.1117/12.2036072
Show Author Affiliations
Nuria Teigell Beneitez, Univ. Gent (Belgium)
Jeroen Missinne, Univ. Gent (Belgium)
Jean Schleipen, Philips Research Nederland B.V. (Netherlands)
Joke Orsel, Philips Research Nederland B.V. (Netherlands)
Menno W. J. Prins, Philips Research Nederland B.V. (Netherlands)
Geert Van Steenberge, Univ. Gent (Belgium)

Published in SPIE Proceedings Vol. 8954:
Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XI
Alexander N. Cartwright; Dan V. Nicolau, Editor(s)

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