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Proceedings Paper

Fluorescence imaging photodetection of early cancer in the bronchi with mTHPC and in the bladder with ALA-induced protoporphyrin IX: preliminary clinical results
Author(s): Martin Forrer; Jerome C. Mizeret; Daniel Braichotte; Georges A. Wagnieres; Jean-Francois Savary; Philippe Monnier; Patrice Jichlinski; Hans-Juerg Leisinger M.D.; Hubert van den Bergh
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Paper Abstract

Clinical results obtained endoscopically with an imaging fluorescence photodetection apparatus based on the use of one excitation wavelength and detection of the fluorescence emission performed in two separate spectral windows are presented. Early cancer photodetection of micro-invasive and in situ carcinoma of the bronchial mucosa after intravenous injection of meso-tetrahydroxyphenylchlorin (m-THPC) was performed during sessions involving photodynamic therapy. Preliminary results are also presented in the context of detecting transitional cell carcinoma of the bladder performed by fluorescence imaging photodetection of protoporphyrin IX (PPIX) following topical application of 5-delta aminolevulinic acid (ALA).

Paper Details

Date Published: 1 March 1995
PDF: 6 pages
Proc. SPIE 2371, 5th International Photodynamic Association Biennial Meeting, (1 March 1995); doi: 10.1117/12.203434
Show Author Affiliations
Martin Forrer, Swiss Federal Institute of Technology (Switzerland)
Jerome C. Mizeret, Swiss Federal Institute of Technology (Switzerland)
Daniel Braichotte, Swiss Federal Institute of Technology (Switzerland)
Georges A. Wagnieres, Swiss Federal Institute of Technology (Switzerland)
Jean-Francois Savary, CHUV Hospital (Switzerland)
Philippe Monnier, CHUV Hospital (Switzerland)
Patrice Jichlinski, CHUV Hospital (Switzerland)
Hans-Juerg Leisinger M.D., CHUV Hospital (Switzerland)
Hubert van den Bergh, Swiss Federal Institute of Technology (Switzerland)

Published in SPIE Proceedings Vol. 2371:
5th International Photodynamic Association Biennial Meeting
Denis A. Cortese, Editor(s)

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