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Proceedings Paper

Preliminary report of clinical application of hematoporphyrin monomethyl ether in photodynamic therapy for alimentary cancers
Author(s): Ying Gu M.D.; Junheng Li M.D.; De-Yu Xu; Zi-Qi Zhang; Yingcai Huang; Kai Wang
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Paper Abstract

A new sensitizer, hematoporphyrin monomethyl ether (HMME), purified by the Second Military Medical University was used with a gold vapor laser for PDT in 8 cases of alimentary cancers. The results showed that 2 cases of early stage gastric cancer and 1 case of rectal polyps with malignancy revealed CR, SR was obtained in 1 case of esophageal cancer and 4 others were MR. No sunburn occurred within the 8 patients who received 12 doses of HMME at 5 mg/kg 2 - 3 hours prior to laser treatment and who were kept away from sun light only 6 hours. Hematoporphyrin monomethyl ether is an effective single compound and safer for PDT.

Paper Details

Date Published: 1 March 1995
PDF: 3 pages
Proc. SPIE 2371, 5th International Photodynamic Association Biennial Meeting, (1 March 1995); doi: 10.1117/12.203381
Show Author Affiliations
Ying Gu M.D., Chinese PLA General Hospital (China)
Junheng Li M.D., Chinese PLA General Hospital (China)
De-Yu Xu, Second Military Medical Univ. (China)
Zi-Qi Zhang, Chinese PLA General Hospital (China)
Yingcai Huang, Chinese PLA General Hospital (China)
Kai Wang, Chinese PLA General Hospital (China)

Published in SPIE Proceedings Vol. 2371:
5th International Photodynamic Association Biennial Meeting
Denis A. Cortese, Editor(s)

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