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Proceedings Paper

Influence of chain lengths of liquid crystals on cholic acid detection
Author(s): Sihui He; Wenlang Liang; Jiyu Fang; Shin-Tson Wu
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Paper Abstract

The concentration level of bile acids is a useful indicator for the diagnosis of liver diseases since individual suffering from liver diseases often has a sharp increase in bile acid concentration. Here we present a sensor platform based on the anchoring transition of nematic liquid crystal (LC), 4’, 4-alkylcyanobiphenyls (nCB, n=5-8), at the surfactant-laden LC/aqueous interfaces for the detection of cholic acid (CA) in aqueous solution. In the sensor platform, the competitive adsorption of CA at the surfactant-laden LC/aqueous interface triggers a homeotropic-to-planar anchoring transition of the LC at the interface. We find the detection limit, which is the minimum concentration of CA required to trigger the LC transition, increases with the increase of the chain length of nCB.

Paper Details

Date Published: 12 September 2013
PDF: 6 pages
Proc. SPIE 8828, Liquid Crystals XVII, 88281G (12 September 2013); doi: 10.1117/12.2032202
Show Author Affiliations
Sihui He, CREOL, The College of Optics and Photonics, Univ. of Central Florida (United States)
Wenlang Liang, Univ. of Central Florida (United States)
Jiyu Fang, Univ. of Central Florida (United States)
Shin-Tson Wu, CREOL, The College of Optics and Photonics, Univ. of Central Florida (United States)

Published in SPIE Proceedings Vol. 8828:
Liquid Crystals XVII
Iam Choon Khoo, Editor(s)

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