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Proceedings Paper

Magnetic trapping of single molecules: principles, developments, and applications
Author(s): W. Grange; T. R. Strick
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Paper Abstract

Over the last decade, magnetic trapping has emerged as a tool which can complement the optical trap in certain key biophysical assays. Through its low cost, ease of use, stability and scalability, magnetic trapping is an attractive tool for micro-rheological analysis, generation of sorting structures for microfluidics, and also single-molecule experimentation. Here we will compare and contrast optical and magnetic trapping as they pertain to singlemolecule experimentation, and in particular to the study of interactions between single molecules such as proteins and nucleic acids.

Paper Details

Date Published: 12 September 2013
PDF: 8 pages
Proc. SPIE 8810, Optical Trapping and Optical Micromanipulation X, 88101H (12 September 2013); doi: 10.1117/12.2027050
Show Author Affiliations
W. Grange, Institut Jacques Monod, CNRS, Univ. Paris Diderot (France)
T. R. Strick, Institut Jacques Monod, CNRS, Univ. Paris Diderot (France)

Published in SPIE Proceedings Vol. 8810:
Optical Trapping and Optical Micromanipulation X
Kishan Dholakia; Gabriel C. Spalding, Editor(s)

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