
Proceedings Paper
Detection of saccharides with a fluorescent sensing device based on a gold film modified with 4-mercaptophenylboronic acid monolayerFormat | Member Price | Non-Member Price |
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Paper Abstract
An extremely sensitive fluorescent sensor based on a phenylboronic acid monolayer was developed for detecting
saccharide molecules. The fluorescent sensor was prepared by assembling a monolayer of 4-mercaptophenylboronic
acid (4-MPBA) onto a gold-coated compact disk. The change in the fluorescence of the 4-MPBA monolayer was
extremely obvious in basic methanolic buffer containing monosaccharides down to the picomolar level. The
fluorescence spectra demonstrated that the 4-MPBA monolayer was sensitive to monosaccharides and disaccharides, and
the affinity of the monolayer toward saccharides was in the order of glucose < fructose < mannose < galactose < maltose > lactose > sucrose. Additionally, the fluorescence intensity of 4-MPBA monolayer was restorable after cleaning with weak acid, indicating that the reported fluorescent sensor with the detection limit of glucose down to the picomolar level is reusable for sensing saccharides.
Paper Details
Date Published: 11 September 2013
PDF: 9 pages
Proc. SPIE 8812, Biosensing and Nanomedicine VI, 881210 (11 September 2013); doi: 10.1117/12.2023060
Published in SPIE Proceedings Vol. 8812:
Biosensing and Nanomedicine VI
Hooman Mohseni; Massoud H. Agahi; Manijeh Razeghi, Editor(s)
PDF: 9 pages
Proc. SPIE 8812, Biosensing and Nanomedicine VI, 881210 (11 September 2013); doi: 10.1117/12.2023060
Show Author Affiliations
Shu-Jen Chen, National Kaohsiung Univ. of Applied Sciences (Taiwan)
Jui-Feng Chang, National Kaohsiung Univ. of Applied Sciences (Taiwan)
Nai-Jen Cheng, National Kaohsiung Univ. of Applied Sciences (Taiwan)
Jui-Feng Chang, National Kaohsiung Univ. of Applied Sciences (Taiwan)
Nai-Jen Cheng, National Kaohsiung Univ. of Applied Sciences (Taiwan)
Jeng-Nan Yih, National Kaohsiung Univ. of Applied Sciences (Taiwan)
Kuo-Chi Chiu, Industrial Technology Research Institute (Taiwan)
Kuo-Chi Chiu, Industrial Technology Research Institute (Taiwan)
Published in SPIE Proceedings Vol. 8812:
Biosensing and Nanomedicine VI
Hooman Mohseni; Massoud H. Agahi; Manijeh Razeghi, Editor(s)
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