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Proceedings Paper

Characterization of a bioinspired elastin-polypropylene fumarate material for vascular prostheses applications
Author(s): Silvia Scaglione; Rossella Barenghi; Szabolcs Beke; Luca Ceseracciu; Ilaria Romano; Francesca Sbrana; Paola Stagnaro; Fernando Brandi; Massimo Vassalli
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Paper Abstract

Vascular prostheses are widely used devices fundamental to avoid the effect of life-threatening diseases and defects. Besides a long experience in the fabrication of biomaterials for vascular applications, many issues still remain unattended. In particular, obtaining a bio-resorbable and bio-active scaffold is a challenge of paramount importance. We present a novel application in which a promising biodegradable polymer, poly-propylene fumarate (PPF), is printed using three dimensional laser-induced cross-linking micromachining device. To enhance the biological role of the scaffold, a bio-inspired approach was taken, by coating the surface of the PPF with elastin, the main constituent of the innermost layer of natural veins and arteries.

Paper Details

Date Published: 23 May 2013
PDF: 6 pages
Proc. SPIE 8792, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials, 87920H (23 May 2013); doi: 10.1117/12.2021754
Show Author Affiliations
Silvia Scaglione, Consiglio Nazionale delle Ricerche (Italy)
Rossella Barenghi, Consiglio Nazionale delle Ricerche (Italy)
Szabolcs Beke, Istituto Italiano di Tecnologia (Italy)
Luca Ceseracciu, Istituto Italiano di Tecnologia (Italy)
Ilaria Romano, Istituto Italiano di Tecnologia (Italy)
Francesca Sbrana, Consiglio Nazionale delle Ricerche (Italy)
Paola Stagnaro, Consiglio Nazionale delle Ricerche (Italy)
Fernando Brandi, Istituto Italiano di Tecnologia (Italy)
Massimo Vassalli, Consiglio Nazionale delle Ricerche (Italy)

Published in SPIE Proceedings Vol. 8792:
Optical Methods for Inspection, Characterization, and Imaging of Biomaterials
Pietro Ferraro; Monika Ritsch-Marte; Simonetta Grilli; David Stifter, Editor(s)

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