Share Email Print

Proceedings Paper

Non-invasive microsensors for studying cell/tissue physiology
Author(s): D. C. Vanegas; M. Taguchi; P. Chaturvedi; S. Burrs; E. S. McLamore
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

Non-invasive tools that allow real-time quantification of molecules relevant to metabolism, homeostasis, and cell signaling in cells and tissue are of great importance for studying physiology. Several microsensor technologies have been developed to monitor concentration of molecules such as ions, oxygen, electroactive molecules (e.g., nitric oxide, hydrogen peroxide), and biomolecules (e.g., sugars, hormones). The major challenges for microsensors are overcoming relatively low sensitivity and low signal-to-noise ratio. Modern approaches for enhancing microsensor performance focus on the incorporation of catalytic nanomaterials to increase sensitivity, reduce response time, and increase operating range. To improve signal-to-noise ratio, a non-invasive microsensor modality called self-referencing (SR) is being applied. The SR technique allows measurement of temporal and spatial transport dynamics at the cell, tissue, organ, and organismal level.

Paper Details

Date Published: 31 May 2013
PDF: 6 pages
Proc. SPIE 8719, Smart Biomedical and Physiological Sensor Technology X, 87190N (31 May 2013); doi: 10.1117/12.2016233
Show Author Affiliations
D. C. Vanegas, Univ. of Florida (United States)
Ciudad Univ. Meléndez (Colombia)
M. Taguchi, Univ. of Florida (United States)
P. Chaturvedi, Univ. of Florida (United States)
S. Burrs, Univ. of Florida (United States)
E. S. McLamore, Univ. of Florida (United States)

Published in SPIE Proceedings Vol. 8719:
Smart Biomedical and Physiological Sensor Technology X
Brian M. Cullum; Eric S. McLamore, Editor(s)

© SPIE. Terms of Use
Back to Top
Sign in to read the full article
Create a free SPIE account to get access to
premium articles and original research
Forgot your username?