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Proceedings Paper

A hybrid plasmonic whispering gallery mode sensor for single bionanoparticle detection
Author(s): S. Holler; V. R. Dantham; V. Kolchenko; Z. Wan; S. Arnold
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Paper Abstract

Our hybrid plasmonic whispering gallery mode biosensor has recently demonstrated detection and characterization of the smallest known RNA virus. A gold nanoparticle affixed to the resonator surface acts like a nanoscopic antenna, enhancing locally the electric field within the cavity mode. When a target analyte binds with this nanoscopic antenna the result is an enhanced response (spectral shift) of the resonator system to the binding event. We have observed shift enhancements ~70× over the response of the bare resonator, thereby permitting the detection and characterization of all known viral particles and even some large protein molecules.

Paper Details

Date Published: 29 May 2013
PDF: 7 pages
Proc. SPIE 8722, Fiber Optic Sensors and Applications X, 87220T (29 May 2013); doi: 10.1117/12.2015506
Show Author Affiliations
S. Holler, Fordham Univ. (United States)
V. R. Dantham, Polytechnic Institute of New York Univ. (United States)
V. Kolchenko, New York City College of Technology (United States)
Z. Wan, Hunter College (United States)
S. Arnold, Polytechnic Institute of New York Univ. (United States)

Published in SPIE Proceedings Vol. 8722:
Fiber Optic Sensors and Applications X
Eric Udd; Gary Pickrell; Henry H. Du; Jerry J. Benterou; Xudong Fan; Alexis Mendez; Stephen J. Mihailov; Anbo Wang; Hai Xiao, Editor(s)

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