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Proceedings Paper

Quantitative and qualitative analysis of fluorescent substances and binary mixtures by use of shifted excitation Raman difference spectroscopy
Author(s): Boris L. Volodin; Sergei Dolgy; Chad Lieber; Huawen Wu; William Yang
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Paper Abstract

Shifted Excitation Raman Difference Spectroscopy (SERDS) implemented with two wavelength-stabilized laser diodes with fixed wavelength separation is discussed as an effective method for dealing with the effects of fluorescence in Raman spectroscopic analysis. In this presentation we discuss the results of both qualitative and quantitative SERDS analysis of a variety of strongly fluorescing samples, including binary liquid mixtures. This application is enabled by the Volume Bragg Grating® (VBG®) technology, which allows manufacturing of compact low-cost high-power laser sources, suitable for extending the SERDS methodology to portable Raman spectrometers.

Paper Details

Date Published: 22 March 2013
PDF: 9 pages
Proc. SPIE 8572, Advanced Biomedical and Clinical Diagnostic Systems XI, 857211 (22 March 2013); doi: 10.1117/12.2008241
Show Author Affiliations
Boris L. Volodin, PD-LD Inc. (United States)
Sergei Dolgy, PD-LD Inc. (United States)
Chad Lieber, BaySpec, Inc. (United States)
Huawen Wu, BaySpec, Inc. (United States)
William Yang, BaySpec, Inc. (United States)

Published in SPIE Proceedings Vol. 8572:
Advanced Biomedical and Clinical Diagnostic Systems XI
Anita Mahadevan-Jansen; Tuan Vo-Dinh; Warren S. Grundfest M.D., Editor(s)

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