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Proceedings Paper

Exact confidence intervals for channelized Hotelling observer performance
Author(s): Adam Wunderlich; Frederic Noo; Marta Heilbrun
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Paper Abstract

Task-based assessments of image quality constitute a rigorous, principled approach to the evaluation of imaging system performance. To conduct such assessments, it has been recognized that mathematical model observers are very useful, particularly for purposes of imaging system development and optimization. One type of model observer that has been widely applied in the medical imaging community is the channelized Hotelling observer (CHO). In the present work, we address the need for reliable confidence interval estimators of CHO performance. Specifically, we observe that a procedure proposed by Reiser for interval estimation of the Mahalanobis distance can be applied to obtain confidence intervals for CHO performance. In addition, we find that these intervals are well-defined with theoretically-exact coverage probabilities, which is a new result not proved by Reiser. The confidence intervals are tested with Monte Carlo simulation and demonstrated with an example comparing x-ray CT reconstruction strategies.

Paper Details

Date Published: 28 March 2013
PDF: 8 pages
Proc. SPIE 8673, Medical Imaging 2013: Image Perception, Observer Performance, and Technology Assessment, 86730I (28 March 2013); doi: 10.1117/12.2008131
Show Author Affiliations
Adam Wunderlich, The Univ. of Utah (United States)
U.S. Food and Drug Administration (United States)
Frederic Noo, The Univ. of Utah (United States)
Marta Heilbrun, The Univ. of Utah (United States)

Published in SPIE Proceedings Vol. 8673:
Medical Imaging 2013: Image Perception, Observer Performance, and Technology Assessment
Craig K. Abbey; Claudia R. Mello-Thoms, Editor(s)

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