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Proceedings Paper

Characterization of T2 hyperintensity lesions in patients with mild traumatic brain injury
Author(s): Jesus J. Caban; Savannah A. Green; Gerard Riedy
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Paper Abstract

Mild traumatic brain injury (TBI) is often an invisible injury that is poorly understood and its sequelae can be difficult to diagnose. Recent neuroimaging studies on patients diagnosed with mild TBI (mTBI) have demonstrated an increase in hyperintense brain lesions on T2-weighted MR images. This paper presents an in-depth analysis of the multi-modal and morphological properties of T2 hyperintensity lesions among service members diagnosed with mTBI. A total of 790 punctuate T2 hyperintensity lesions from 89 mTBI subjects were analyzed and used to characterize the lesions based on different quantitative measurements. Morphological analysis shows that on average, T2 hyperintensity lesions have volumes of 23mm3 (±24.75), a roundness measure of 0.83 (±0.08) and an elongation of 7.90 (±2.49). The frontal lobe lesions demonstrated significantly more elongated lesions when compared to other areas of the brain.

Paper Details

Date Published: 18 March 2013
PDF: 6 pages
Proc. SPIE 8670, Medical Imaging 2013: Computer-Aided Diagnosis, 86702U (18 March 2013); doi: 10.1117/12.2008117
Show Author Affiliations
Jesus J. Caban, Walter Reed National Military Medical Ctr. (United States)
Savannah A. Green, Franklin & Marshall College (United States)
Gerard Riedy, Walter Reed National Military Medical Ctr. (United States)

Published in SPIE Proceedings Vol. 8670:
Medical Imaging 2013: Computer-Aided Diagnosis
Carol L. Novak; Stephen Aylward, Editor(s)

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