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Proceedings Paper

A dynamic dosimetry system for prostate brachytherapy
Author(s): Nathanael Kuo; Ehsan Dehghan; Anton Deguet; Danny Y. Song; Jerry L. Prince; Junghoon Lee
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Paper Abstract

The lack of dynamic dosimetry tools for permanent prostate brachytherapy causes otherwise avoidable problems in prostate cancer patient care. The goal of this work is to satisfy this need in a readily adoptable manner. Using the ubiquitous ultrasound scanner and mobile non-isocentric C-arm, we show that dynamic dosimetry is now possible with only the addition of an arbitrarily configured marker-based fiducial. Not only is the system easily configured from accessible hardware, but it is also simple and convenient, requiring little training from technicians. Furthermore, the proposed system is built upon robust algorithms of seed segmentation, fiducial detection, seed reconstruction, and image registration. All individual steps of the pipeline have been thoroughly tested, and the system as a whole has been validated on a study of 25 patients. The system has shown excellent results of accurately computing dose, and does so with minimal manual intervention, therefore showing promise for widespread adoption of dynamic dosimetry.

Paper Details

Date Published: 8 March 2013
PDF: 6 pages
Proc. SPIE 8671, Medical Imaging 2013: Image-Guided Procedures, Robotic Interventions, and Modeling, 867109 (8 March 2013); doi: 10.1117/12.2008097
Show Author Affiliations
Nathanael Kuo, Johns Hopkins Univ. (United States)
Ehsan Dehghan, Philips Research North America (United States)
Anton Deguet, Johns Hopkins Univ. (United States)
Danny Y. Song, Johns Hopkins Univ. (United States)
Jerry L. Prince, Johns Hopkins Univ. (United States)
Junghoon Lee, Johns Hopkins Univ. (United States)

Published in SPIE Proceedings Vol. 8671:
Medical Imaging 2013: Image-Guided Procedures, Robotic Interventions, and Modeling
David R. Holmes III; Ziv R. Yaniv, Editor(s)

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