
Proceedings Paper
Cardiac deformation indices derived from motion estimated x-ray computed tomographyFormat | Member Price | Non-Member Price |
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Paper Abstract
Cardiac deformation indices such as strain, strain rate, and time to maximal strain are valuable in early detection of heart
disease and hold tremendous prognostic value in assessing patients recovering from heart failure. These indices have
been previously measured in modalities such as Doppler echocardiography and magnetic resonance imaging. However,
cardiac deformation has not been well characterized in X-ray computed tomography (CT), a modality whose balance of
high acquisition speed and good temporal and spatial resolution makes it highly desirable in the clinical setting. The
current work, an extension of our group’s previously published cardiac motion estimation algorithm, calculates
deformation indices such as strain, strain rate, maximum strain, and time to maximal strain from four-dimensional
motion vector field data. Along each dimension, calculations are made between every adjacent pair of grid points, thus
striving for simplicity while yielding an increase in spatial resolution over approaches that divide the heart into a number
of segments. Results are visualized as semi-transparent color maps superimposed on CT image slices in the short-axis
view and the two long-axis views. Results agree with the expected behavior of myocardial contraction. Animal studies
are underway to better assess the physiologic accuracy of the calculated deformation indices as well as to compare the
results with those from other imaging modalities. The present work and its further refinements may yield rich yet easily
accessible information for clinicians in early diagnosis and follow-up monitoring.
Paper Details
Date Published: 19 March 2013
PDF: 6 pages
Proc. SPIE 8668, Medical Imaging 2013: Physics of Medical Imaging, 86682N (19 March 2013); doi: 10.1117/12.2008079
Published in SPIE Proceedings Vol. 8668:
Medical Imaging 2013: Physics of Medical Imaging
Robert M. Nishikawa; Bruce R. Whiting; Christoph Hoeschen, Editor(s)
PDF: 6 pages
Proc. SPIE 8668, Medical Imaging 2013: Physics of Medical Imaging, 86682N (19 March 2013); doi: 10.1117/12.2008079
Show Author Affiliations
Liwei Jiang, Johns Hopkins Univ. School of Medicine (United States)
Qiulin Tang, Johns Hopkins Univ. School of Medicine (United States)
Qiulin Tang, Johns Hopkins Univ. School of Medicine (United States)
Katsuyuki Taguchi, Johns Hopkins Univ. School of Medicine (United States)
Published in SPIE Proceedings Vol. 8668:
Medical Imaging 2013: Physics of Medical Imaging
Robert M. Nishikawa; Bruce R. Whiting; Christoph Hoeschen, Editor(s)
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