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Proceedings Paper

Automated segmentation of brain ventricles in unenhanced CT of patients with ischemic stroke
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Paper Abstract

We are developing an automated method for detection and quantification of ischemic stroke in computed tomography (CT). Ischemic stroke often connects to brain ventricle, therefore, ventricular segmentation is an important and difficult task when stroke is present, and is the topic of this study. We first corrected inclination angle of brain by aligning midline of brain with the vertical centerline of a slice. We then estimated the intensity range of the ventricles by use of the k-means method. Two segmentation of the ventricle were obtained by use of thresholding technique. One segmentation contains ventricle and nearby stroke. The other mainly contains ventricle. Therefore, the stroke regions can be extracted and removed using image difference technique. An adaptive template-matching algorithm was employed to identify objects in the fore-mentioned segmentation. The largest connected component was identified and considered as the ventricle. We applied our method to 25 unenhanced CT scans with stroke. Our method achieved average Dice index, sensitivity, and specificity of 95.1%, 97.0%, and 99.8% for the entire ventricular regions. The experimental results demonstrated that the proposed method has great potential in detection and quantification of stroke and other neurologic diseases.

Paper Details

Date Published: 28 February 2013
PDF: 7 pages
Proc. SPIE 8670, Medical Imaging 2013: Computer-Aided Diagnosis, 86702P (28 February 2013); doi: 10.1117/12.2007775
Show Author Affiliations
Xiaohua Qian, Duke Univ. Medical Ctr. (United States)
Jilin Univ. (China)
Jiahui Wang, The Univ. of North Carolina at Chapel Hill (United States)
Qiang Li, Duke Univ. Medical Ctr. (United States)
Shanghai Advanced Research Institute (China)

Published in SPIE Proceedings Vol. 8670:
Medical Imaging 2013: Computer-Aided Diagnosis
Carol L. Novak; Stephen Aylward, Editor(s)

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