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Proceedings Paper

Tumor segmentation in brain MRI by sparse optimization
Author(s): Shandong Wu; David J. Rippe; Nicholas G. Avgeropoulos
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Paper Abstract

In this work we propose a novel method for brain tumor segmentation in MRI by adapting the sparse optimization techniques. The core of the method lies in the subspace decomposition of the tissue feature space constituted by the brain MR images. The tumor-grown MRI slices can be viewed as a corrupted observation, which therefore can be decomposed into two components: the low-rank normal brain tissue structures and the sparse corruption/error that is due to the developed tumor. Through performing rank decomposition the corruption/error can be spotted out, thus giving rise to an initial segmentation of tumor. Our method requires no model learning. Experiments are performed on a data set of 12 subjects and the segmentation agreement is 0.86 in terms of the Dice’s similarity coefficient in comparison with the manual segmentation that is performed by a 15-year experienced radiologist. The proposed method represents an efficient mode for brain tumor segmentation that may be potentially incorporated in automated or semi-automatic segmentation systems in the clinical workflow.

Paper Details

Date Published: 13 March 2013
PDF: 6 pages
Proc. SPIE 8669, Medical Imaging 2013: Image Processing, 86691H (13 March 2013); doi: 10.1117/12.2007086
Show Author Affiliations
Shandong Wu, Univ. of Pennsylvania (United States)
David J. Rippe, Florida Hospital Zephyrhills (United States)
Nicholas G. Avgeropoulos, M.D. Anderson Cancer Ctr. (United States)

Published in SPIE Proceedings Vol. 8669:
Medical Imaging 2013: Image Processing
Sebastien Ourselin; David R. Haynor, Editor(s)

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