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Proceedings Paper

Phase-function corrected diffusion model for diffuse reflectance of a pencil beam obliquely incident on a semi-infinite turbid medium
Author(s): Roger J. Zemp
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Paper Abstract

Oblique incidence reflectometry (OIR) is an established technique for estimation of tissue optical properties, however, a sensing footprint of a few transport mean-free paths is often needed when diffusion-regime-based algorithms are used. Smaller-footprint probes require improved light-propagation models and inversion schemes for diffuse reflectance close to the point-of-entry but might enable micro-endoscopic form factors for clinical assessments of cancers and pre-cancers. In this paper we extend the phase-function corrected diffusion-theory presented by Vitkin et al. (Nat. Comm 2011) to the case of pencil beams obliquely incident on a semi-infinite turbid medium. The model requires minimal computational resources and offers improved accuracy over more traditional diffusion-theory approximations models when validated against Monte Carlo simulations. The computationally efficient nature of the models may lend themselves to rapid fitting procedures for inverse problems.

Paper Details

Date Published: 21 February 2013
PDF: 8 pages
Proc. SPIE 8592, Biomedical Applications of Light Scattering VII, 85920I (21 February 2013); doi: 10.1117/12.2005036
Show Author Affiliations
Roger J. Zemp, Univ. of Alberta (Canada)

Published in SPIE Proceedings Vol. 8592:
Biomedical Applications of Light Scattering VII
Adam P. Wax; Vadim Backman, Editor(s)

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