During the cardiac development, the cardiac wall and the blood flow actively interact with each other, and determine the biomechanical environment to which the embryonic heart exposes. Employing an ultrafast 1310nm-band dual-camera spectral domain optical coherence tomography (SDOCT), the radial strain rate of the myocardial wall can be extracted with high signal-to-noise ratio, at the same time the Doppler velocity of the blood flow can also be displayed. The ability to simultaneously characterize these two cardiac tissues provides a powerful approach to better understand the interaction between the cardiac wall and the blood flow, which is important to the investigation of cardiac development.

Date Published: 26 March 2013
PDF: 8 pages
Proc. SPIE 8593, Optical Methods in Developmental Biology, 859304 (26 March 2013); doi: 10.1117/12.2004773

Published in SPIE Proceedings Vol. 8593:
Optical Methods in Developmental Biology
Andrew M. Rollins; Cecilia Lo; Scott E. Fraser, Editor(s)