
Proceedings Paper
Video-rate photoacoustic microscopy of micro-vasculaturesFormat | Member Price | Non-Member Price |
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Paper Abstract
We report the development of photoacoustic microscopy capable of video-rate high-resolution in-vivo
imaging in deep tissue. A lightweight photoacoustic probe is made of a single-element
broadband ultrasound transducer, a compact photoacoustic beam combiner, and a bright-field light
delivery system. Focused broadband ultrasound detection provides a 44-μm lateral resolution and a
28-μm axial resolution. A multimode optical fiber is used to deliver laser pulses. The bright-field
light delivery system can effectively improve the illumination efficiency. The photoacoustic probe
weighs less than 40 grams and is mounted on a voice-coil scanner to acquire 40 cross-sectional
images per second over several-mm range. The fast speed can effectively improve imaging
throughput, reduce motion artifacts, and enable the visualization of highly dynamic biomedical
processes. High-resolution micro-vascular imaging is successfully demonstrated.
Paper Details
Date Published: 4 March 2013
PDF: 6 pages
Proc. SPIE 8581, Photons Plus Ultrasound: Imaging and Sensing 2013, 85811T (4 March 2013); doi: 10.1117/12.2004714
Published in SPIE Proceedings Vol. 8581:
Photons Plus Ultrasound: Imaging and Sensing 2013
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)
PDF: 6 pages
Proc. SPIE 8581, Photons Plus Ultrasound: Imaging and Sensing 2013, 85811T (4 March 2013); doi: 10.1117/12.2004714
Show Author Affiliations
Lidai Wang, Washington Univ. in St. Louis (United States)
Konstantin Maslov, Washington Univ. in St. Louis (United States)
Wenxin Xing, Washington Univ. in St. Louis (United States)
Konstantin Maslov, Washington Univ. in St. Louis (United States)
Wenxin Xing, Washington Univ. in St. Louis (United States)
Alejandro Garcia-Uribe, Washington Univ. in St. Louis (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)
Published in SPIE Proceedings Vol. 8581:
Photons Plus Ultrasound: Imaging and Sensing 2013
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)
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