
Proceedings Paper
Natural motion of the optic nerve head revealed by high speed phase-sensitive OCTFormat | Member Price | Non-Member Price |
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Paper Abstract
We use phase-sensitive optical coherence tomography (OCT) to measure the deformation of the optic nerve head during
the pulse cycle, motivated by the possibility that these deformations might be indicative of the progression of glaucoma.
A spectral-domain OCT system acquired 100k A-scans per second, with measurements from a pulse-oximeter recorded
simultaneously, correlating OCT data to the subject’s pulse. Data acquisition lasted for 2 seconds, to cover at least two
pulse cycles. A frame-rate of 200–400 B-scans per second results in a sufficient degree of correlated speckle between
successive frames that the phase-differences between fames can be extracted. Bulk motion of the entire eye changes the
phase by several full cycles between frames, but this does not severely hinder extracting the smaller phase-changes due
to differential motion within a frame. The central cup moves about 5 μm/s relative to the retinal-pigment-epithelium
edge, with tissue adjacent to blood vessels showing larger motion.
Paper Details
Date Published: 26 March 2013
PDF: 9 pages
Proc. SPIE 8567, Ophthalmic Technologies XXIII, 85670M (26 March 2013); doi: 10.1117/12.2004000
Published in SPIE Proceedings Vol. 8567:
Ophthalmic Technologies XXIII
Fabrice Manns; Per G. Söderberg; Arthur Ho, Editor(s)
PDF: 9 pages
Proc. SPIE 8567, Ophthalmic Technologies XXIII, 85670M (26 March 2013); doi: 10.1117/12.2004000
Show Author Affiliations
Published in SPIE Proceedings Vol. 8567:
Ophthalmic Technologies XXIII
Fabrice Manns; Per G. Söderberg; Arthur Ho, Editor(s)
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