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Proceedings Paper

A non-destructive diffuse reflectance calibration-free method to determine optical parameters of biological tissues
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Paper Abstract

A method for non-destructive determination of absorption and transport (reduced) scattering coefficients of turbid media (biological tissue, first of all) is presented. It refers to the spatially resolved diffuse reflectance techniques with optical fiber probe. The method is based on a more accurate (in comparison with diffusion) two parameters kinetic light propagation model and a special two step non-analog Monte Carlo technique, it involves no additional parameters and uses no assumptions about spectral dependencies of the coefficients, allows application of monochrome sources and probes with minimally possible number of reading fibers (only 2), goes without calibration phantoms and measurements. Numerical and experimental testing have showed the measured coefficients provide a good prediction of both light reflection and penetration fields in semi-infinite homogeneous media with low-mid absorption.

Paper Details

Date Published: 15 February 2013
PDF: 14 pages
Proc. SPIE 8579, Optical Interactions with Tissue and Cells XXIV, 857912 (15 February 2013); doi: 10.1117/12.2003718
Show Author Affiliations
Alexander V. Lappa, Chelyabinsk State Univ. (Russian Federation)
Artem N. Kulikovskiy, Chelyabinsk State Univ. (Russian Federation)
Anton N. Kulikovskiy, Chelyabinsk State Univ. (Russian Federation)
Tamara A. Makarova, Chelyabinsk State Univ. (Russian Federation)

Published in SPIE Proceedings Vol. 8579:
Optical Interactions with Tissue and Cells XXIV
E. Duco Jansen; Robert J. Thomas, Editor(s)

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