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Proceedings Paper

A method to visualize lipid distribution within arterial vessel walls by 1.7 µm spectroscopic spectral-domain optical coherence tomography
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Paper Abstract

We report a method to visualize lipid distribution in axial and lateral direction within arterial vessel walls by spectroscopic spectral-domain Optical Coherence Tomography (OCT) at 1.7 μm wavelength for identification of lipidrich plaque. An OCT interferometric spectrum, after divided into several subbands for each of which A-scan profile is calculated, are fitted to a model accounting the contributions from absorption and scattering, with assumption that lipid content changes slowly in space, and lipid distribution is visualized. We investigated numerically the effects of analyzing parameters on the performance of lipid detection using simulated OCT data, and have found optimum parameters.

Paper Details

Date Published: 22 March 2013
PDF: 7 pages
Proc. SPIE 8572, Advanced Biomedical and Clinical Diagnostic Systems XI, 85720E (22 March 2013); doi: 10.1117/12.2003700
Show Author Affiliations
Mitsuharu Hirano, Sumitomo Electric Industries, Ltd. (Japan)
Ichiro Sogawa, Sumitomo Electric Industries, Ltd. (Japan)
Takemi Hasegawa, Sumitomo Electric Industries, Ltd. (Japan)
Masato Tanaka, Sumitomo Electric Industries, Ltd. (Japan)

Published in SPIE Proceedings Vol. 8572:
Advanced Biomedical and Clinical Diagnostic Systems XI
Anita Mahadevan-Jansen; Tuan Vo-Dinh; Warren S. Grundfest M.D., Editor(s)

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