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Proceedings Paper

Sub-wavelength fluorescent polymer coatings to convert standard glass capillaries into robust microfluidic refractometric sensors
Author(s): Kristopher J. Rowland; Alexandre François; Peter Hoffmann; Tanya M. Monro
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Paper Abstract

A capillary microresonator platform for label-free refractometric sensing is demonstrated by coating the interior of thick-walled silica capillaries with a sub-wavelength layer of high refractive index, dye-doped polymer. No intermediate processing, such as etching or tapering, of the capillary is required. Side illumination and detection of the polymer layer reveals a fluorescence spectrum that is periodically modulated by the presence of whispering gallery modes within the layer. The fabricated capillary resonators exhibited sensitivities to changes in internal refractive index of up to 29.44 nm/RIU, demonstrated by flowing through aqueous dilutions of glucose. Thick walled capillaries are used in order to readily allow interfacing with existing biological and chemical sensing and separation platforms such as capillary electrophoresis or gas chromatography where such capillaries are routinely used. The interior polymer coating method described here could enable the use of a wide range of materials for the design of optofluidic label-free sensors integrated with industry standard (bio)chemical analytical separation platforms.

Paper Details

Date Published: 5 March 2013
PDF: 7 pages
Proc. SPIE 8570, Frontiers in Biological Detection: From Nanosensors to Systems V, 85700E (5 March 2013); doi: 10.1117/12.2003522
Show Author Affiliations
Kristopher J. Rowland, The Univ. of Adelaide (Australia)
Alexandre François, The Univ. of Adelaide (Australia)
Peter Hoffmann, The Univ. of Adelaide (Australia)
Tanya M. Monro, The Univ. of Adelaide (Australia)

Published in SPIE Proceedings Vol. 8570:
Frontiers in Biological Detection: From Nanosensors to Systems V
Benjamin L. Miller; Philippe M. Fauchet, Editor(s)

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