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Proceedings Paper

Measuring non-radiative relaxation time of fluorophores by intensity-modulated laser induced photoacoustic effect
Author(s): Behrouz Soroushian; Xinmai Yang
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Paper Abstract

Most biological chromophores and molecules relax primarily through non-radiative processes; therefore, mapping of relaxation time related to non-rediative process can be a potential indicator of tissue status. In order to map relative nonradiative relaxation time, modulated tone-burst light is used to generate photoacoustic signals. Then nonradiative relaxation time is indicated by the amplitude decay rate as modulation frequency increases. The results show that although blood is an optically weak absorber at 808 nm, by using this method a significant enhancement of contrast-tonoise ratio of a blood target compared to pulsed photoacoustic imaging at this wavelength is achieved.

Paper Details

Date Published: 4 March 2013
PDF: 7 pages
Proc. SPIE 8581, Photons Plus Ultrasound: Imaging and Sensing 2013, 85812V (4 March 2013); doi: 10.1117/12.2003222
Show Author Affiliations
Behrouz Soroushian, Univ. of Kansas (United States)
Xinmai Yang, Univ. of Kansas (United States)

Published in SPIE Proceedings Vol. 8581:
Photons Plus Ultrasound: Imaging and Sensing 2013
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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