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Proceedings Paper

Non-invasive assessment of corneal crosslinking changes using polarization sensitive optical coherence tomography
Author(s): D. Alonso-Caneiro; M. Yamanari; S. Fukuda; S. Hoshi; S. Nagase; T. Oshika; Y. Yasuno; M. Collins
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Paper Abstract

Collagen crosslinking (CXL) has shown promising results in the prevention of the progression of keratoconus and corneal ectasia. However, techniques for in vivo and in situ assessment of the treatment are limited. In this study, ex vivo porcine eyes were treated with a chemical CXL agent (glutaraldehyde), during which polarization sensitive optical coherence tomography (PS-OCT) recordings were acquired simultaneously to assess the sensitivity of the technique to assess changes in the cornea. The results obtained in this study suggest that PSOCT may be a suitable technique to measure CXL changes in situ and to assess the local changes in the treated region of the cornea.

Paper Details

Date Published: 26 March 2013
PDF: 7 pages
Proc. SPIE 8567, Ophthalmic Technologies XXIII, 85670F (26 March 2013); doi: 10.1117/12.2002988
Show Author Affiliations
D. Alonso-Caneiro, Queensland Univ. of Technology (Australia)
M. Yamanari, Tomey Corp. (Japan)
S. Fukuda, Univ. of Tsukuba (Japan)
S. Hoshi, Univ. of Tsukuba (Japan)
S. Nagase, Tokyo Medical Univ. (Japan)
T. Oshika, Univ. of Tsukuba (Japan)
Y. Yasuno, Univ. of Tsukuba (Japan)
M. Collins, Queensland Univ. of Technology (Australia)

Published in SPIE Proceedings Vol. 8567:
Ophthalmic Technologies XXIII
Fabrice Manns; Per G. Söderberg; Arthur Ho, Editor(s)

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