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Proceedings Paper

Medical applications of fast 3D cameras in real-time image-guided radiotherapy (IGRT) of cancer
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Paper Abstract

Dynamic volumetric medical imaging (4DMI) has reduced motion artifacts, increased early diagnosis of small mobile tumors, and improved target definition for treatment planning. High speed cameras for video, X-ray, or other forms of sequential imaging allow a live tracking of external or internal movement useful for real-time image-guided radiation therapy (IGRT). However, none of 4DMI can track real-time organ motion and no camera has correlated with 4DMI to show volumetric changes. With a brief review of various IGRT techniques, we propose a fast 3D camera for live-video stereovision, an automatic surface-motion identifier to classify body or respiratory motion, a mechanical model for synchronizing the external surface movement with the internal target displacement by combination use of the real-time stereovision and pre-treatment 4DMI, and dynamic multi-leaf collimation for adaptive aiming the moving target. Our preliminary results demonstrate that the technique is feasible and efficient in IGRT of mobile targets. A clinical trial has been initiated for validation of its spatial and temporal accuracies and dosimetric impact for intensity-modulated RT (IMRT), volumetric-modulated arc therapy (VMAT), and stereotactic body radiotherapy (SBRT) of any mobile tumors. The technique can be extended for surface-guided stereotactic needle insertion in biopsy of small lung nodules.

Paper Details

Date Published: 8 March 2013
PDF: 16 pages
Proc. SPIE 8618, Emerging Digital Micromirror Device Based Systems and Applications V, 861802 (8 March 2013); doi: 10.1117/12.2002603
Show Author Affiliations
Shidong Li, Temple Univ. Hospital (United States)
Tuotuo Li, Xigen LLC (United States)
Jason Geng, Xigen LLC (United States)

Published in SPIE Proceedings Vol. 8618:
Emerging Digital Micromirror Device Based Systems and Applications V
Michael R. Douglass; Patrick I. Oden, Editor(s)

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