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Proceedings Paper

Time-domain schemes of optical topography: methodology, simulative and experimental validation
Author(s): Linjing Duan; Xin Wang; Jiao Li; Xi Yi; Linhui Wu; Limin Zhang; Feng Gao
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Paper Abstract

To cope with the low quantification in the established optical topography that originates from the excessively simplified computation model based on the modified Lambert-Beer’s Law (MLBL), we propose a least-squares fitting scheme for time-domain optical topography that seeks for data matching between the time-resolved measurement and the model prediction calculated by analytically solving the time-domain diffusion equation in semi-infinite geometry. Our simulative and phantom experiments demonstrate that the proposed curve-fitting method is overall superior to the conventional MLBL-based one in quantitative performance.

Paper Details

Date Published: 13 March 2013
PDF: 10 pages
Proc. SPIE 8574, Multimodal Biomedical Imaging VIII, 85740P (13 March 2013); doi: 10.1117/12.2001978
Show Author Affiliations
Linjing Duan, Tianjin Univ. (China)
Xin Wang, Tianjin Univ. (China)
Jiao Li, Tianjin Univ. (China)
Xi Yi, Tianjin Univ. (China)
Linhui Wu, Tianjin Univ. (China)
Limin Zhang, Tianjin Univ. (China)
Feng Gao, Tianjin Univ. (China)

Published in SPIE Proceedings Vol. 8574:
Multimodal Biomedical Imaging VIII
Fred S. Azar; Xavier Intes, Editor(s)

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