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Proceedings Paper

Laser reflectance oximetry and Doppler flowmetry in assessment of complex physiological parameters of cutaneous blood microcirculation
Author(s): Andrey V. Dunaev; Victor V. Sidorov; Neil A. Stewart; Sergei G. Sokolovski; Edik U. Rafailov
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Paper Abstract

The integration of multiple optical techniques within a single diagnostic device is used to address the difficulties in standardising measurement of cutaneous blood micro-dynamics caused by high variability. We demonstrate the benefits of simultaneous assessment of blood relative volume (Vb), microcirculation index (Im) and tissue oxygen saturation (StO2), during long-term examination of healthy volunteers. Consequently, five rhythmic components: endothelial, neurogenic, myogenic, breath and heart pulses were established showing high variability up to 30 – 50% as well as in initial parameters around 16%. All rhythmic components were synchronous with some latency between Im and StO2 in the myogenic component supports the hypothesis of strong correlation between peripheral hemodynamics and oxygen utilisation in tissues.

Paper Details

Date Published: 22 March 2013
PDF: 9 pages
Proc. SPIE 8572, Advanced Biomedical and Clinical Diagnostic Systems XI, 857205 (22 March 2013); doi: 10.1117/12.2001797
Show Author Affiliations
Andrey V. Dunaev, Univ. of Dundee (United Kingdom)
Victor V. Sidorov, SPE LAZMA Ltd. (Russian Federation)
Neil A. Stewart, Univ. of Dundee (United Kingdom)
Sergei G. Sokolovski, Univ. of Dundee (United Kingdom)
Edik U. Rafailov, Univ. of Dundee (United Kingdom)

Published in SPIE Proceedings Vol. 8572:
Advanced Biomedical and Clinical Diagnostic Systems XI
Anita Mahadevan-Jansen; Tuan Vo-Dinh; Warren S. Grundfest M.D., Editor(s)

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