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Proceedings Paper

A novel assay for rapid HIV-1 protease detection using optical sensors and magnetic carriers
Author(s): Chiheb Esseghaier; Andy Ng; Mohammed Zourob
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Paper Abstract

In this work, a very simple electrochemical HIV-1 protease biosensor useful for the development of an inexpensive lab-on-a- chip (LOC) device was constructed. The detection mechanism was designed to minimize the complexity either in the recognition receptor immobilization step or during the detection itself. The magnetic self-assembled monolayer of HIV-1 protease substrate peptide was able to detect as low as 10 pg/ml of the protease within 25 minutes with high specificity.

Paper Details

Date Published: 24 October 2012
PDF: 6 pages
Proc. SPIE 8412, Photonics North 2012, 841209 (24 October 2012); doi: 10.1117/12.2001479
Show Author Affiliations
Chiheb Esseghaier, Institut National de la Recherche Scientifique (Canada)
Andy Ng, Institut National de la Recherche Scientifique (Canada)
Mohammed Zourob, Institut National de la Recherche Scientifique (Canada)

Published in SPIE Proceedings Vol. 8412:
Photonics North 2012
Jean-Claude Kieffer, Editor(s)

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