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Proceedings Paper

Endoscopic laser treatment for rectosigmoid villous adenoma: factors effecting the results
Author(s): Jean Marc Brunetaud; Vincent Maunoury M.D.; Dominique Cochelard; Brigitte Boniface
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Paper Abstract

This present work reports the long term results after endoscopic laser treatment in 474 patients with benign rectosigmoid villous adenomas revealed by biopsy. Two types of wavelength were used: The 1.06 micrometers infrared light from the Nd:YAG laser and the green light from the argon laser or the Nd:YAG frequency doubled laser. In some patients, both wavelengths were used. Treatment was completed in 415 patients. Total tumor destruction was obtained in 92.8% of them, a carcinoma was detected in 6.5% on biopsy specimens obtained during laser treatment, and benign villous tissue persisted in 0.7%. During the average 30 mo. follow up period of the patients with total tumor destruction, 18% had a tumor recurrence. Treatment was well tolerated with a 1.8% complication rate (one perforation, one hemorrhage, and 7 stenosis requiring dilatation). Because treatment is long and difficult and cancer rate is high, endoscopic laser should be limited in patients with a circumferential villous adenoma to nonsurgical candidates. The risk of complication after surgery (some being fatal) has to be balanced against the risk of undetected carcinoma in the other patients and the indication for endoscopic laser treatment should be discussed case by case.

Paper Details

Date Published: 23 December 1994
PDF: 12 pages
Proc. SPIE 2327, Medical Applications of Lasers II, (23 December 1994); doi: 10.1117/12.197587
Show Author Affiliations
Jean Marc Brunetaud, Institut National de la Sante et de la Recherche Medicale and Hopital Huriez (France)
Vincent Maunoury M.D., Institut National de la Sante et de la Recherche Medicale (France)
Dominique Cochelard, Laboratorie de Biomathematiques/Faculte de Pharmacie (France)
Brigitte Boniface, Laboratorie de Biomathematiques/Faculte de Pharmacie (France)

Published in SPIE Proceedings Vol. 2327:
Medical Applications of Lasers II
Stephen G. Bown; J. Escourrou; Frank Frank; Herbert J. Geschwind M.D.; Guilhem Godlewski M.D.; Frederic Laffitte; Hans H. Scherer M.D., Editor(s)

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