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Proceedings Paper

Feasibility studies for laser solder neurorrhaphy
Author(s): Lawrence S. Bass M.D.; Nader Moazami M.D.; Anthony Avellino; W. Trosaborg; Michael R. Treat M.D.
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Paper Abstract

We present a novel technique of nerve repair attempting to reduce scarring and improve alignment. A laser solder composed of albumin, hyaluronate, and indocyanine green dye (peak absorbance 805 nm) was used. After applying solder to the anastomotic site, nerve ends can be precisely aligned and sealed in place using an 810 nm diode laser. Transected sciatic nerves in the rat were used as the experimental model. Laser repairs had approximately half the immediate strength of suture repairs (130 vs 280 g/cm2) but comparable strength by 7 days (270 vs 250 g/cm2). There was no dehiscence in either group. Thermal damage was confined to the solder and epineurium. At 90 days there was no difference in nerve conduction values or axon counts in suture or laser repairs. Histology was suggestive of a later stage of regeneration in the laser group. Laser soldering produces increased strength compared with traditional laser welding with less thermal injury.

Paper Details

Date Published: 7 September 1994
PDF: 4 pages
Proc. SPIE 2128, Laser Surgery: Advanced Characterization, Therapeutics, and Systems IV, (7 September 1994);
Show Author Affiliations
Lawrence S. Bass M.D., New York Univ. Medical Ctr. (United States)
Nader Moazami M.D., Columbia-Presbyterian Medical Ctr. (United States)
Anthony Avellino, Columbia-Presbyterian Medical Ctr. (United States)
W. Trosaborg, Columbia-Presbyterian Medical Ctr. (United States)
Michael R. Treat M.D., Columbia-Presbyterian Medical Ctr. (United States)

Published in SPIE Proceedings Vol. 2128:
Laser Surgery: Advanced Characterization, Therapeutics, and Systems IV
R. Rox Anderson M.D.; R. Rox Anderson M.D., Editor(s)

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