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Proceedings Paper

Time-resolved analysis of laser-induced photothermal stress in blood clots
Author(s): German Da Costa
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Paper Abstract

Blood clots are illuminated with a focused HeNe laser beam at different power levels. The time-varying reflected speckle pattern (which is recorded with a video camera and filed in a computer memory) rapidly changes in the early heating stage and then remains progressively at rest. The difference between pairs of time-consecutive images is measured by adding the squared differences of intensities at corresponding pixels. This allows one to define a speed of variation D(t) of the reflected image. It is shown that the time-law D(t) is similar to the function describing the derivative of sample temperature with respect to heating time (t). This supports the hypothesis that the observed effect is due to thermal dilatation of biological material forming the clot.

Paper Details

Date Published: 17 August 1994
PDF: 11 pages
Proc. SPIE 2137, Time-Resolved Laser Spectroscopy in Biochemistry IV, (17 August 1994); doi: 10.1117/12.182731
Show Author Affiliations
German Da Costa, Univ. Simon Bolivar (Venezuela)

Published in SPIE Proceedings Vol. 2137:
Time-Resolved Laser Spectroscopy in Biochemistry IV
Joseph R. Lakowicz, Editor(s)

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